Propranolol is in a group of medications called beta-blockers. Beta-blockers affect the heart and circulation of blood flow. Propranolol is used to treat tremors, angina (chest pain), hypertension (high blood pressure), heart rhythm disorders, and other heart or circulatory conditions. It is also used to treat or prevent heart attack, and to reduce the severity and frequency of migraine headaches. Propranolol may also be used for purposes other than those listed in this medication guide.